Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture
Author:
Affiliation:
1. Department for Chemistry and Applied Biosciences; ETH Zurich; Zurich Switzerland
2. ChromaCon AG; Zurich Switzerland
Funder
Commission for Technology and Innovation
Publisher
Wiley
Subject
Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/biot.201500223/fullpdf
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3. Continuous downstream processing of biopharmaceuticals;Jungbauer;Trends Biotechnol.,2013
4. Multifraction separation in countercurrent chromatography (MCSGP);Krättli;Biotechnol. Bioeng.,2013
5. A continuous multicolumn countercurrent solvent gradient purification (MCSGP) process;Aumann;Biotechnol. Bioeng.,2007
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