Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Author:

Rafiq Qasim A.123,Coopman Karen1,Nienow Alvin W.14,Hewitt Christopher J.13

Affiliation:

1. Centre for Biological Engineering, Department of Chemical Engineering, Loughborough University; Leicestershire United Kingdom

2. Wolfson School of Manufacturing and Mechanical Engineering, Loughborough University; Leicestershire United Kingdom

3. Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle; Birmingham United Kingdom

4. School of Chemical Engineering, University of Birmingham, Edgbaston; Birmingham United Kingdom

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference44 articles.

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2. Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method;Friedenstein;Exp. Hematol.,1974

3. Multilineage potential of adult human mesenchymal stem cells;Pittenger;Science,1999

4. Mesenchymal stem cells and their potential as cardiac therapeutics;Pittenger;Circ. Res.,2004

5. Human mesenchymal stem cells modulate allogeneic immune cell responses;Aggarwal;Blood,2005

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