Real-time pH monitoring of industrially relevant enzymatic reactions in a microfluidic side-entry reactor (μSER) shows potential for pH control

Author:

Gruber Pia1,Marques Marco P.C.1,Sulzer Philipp2,Wohlgemuth Roland3,Mayr Torsten2,Baganz Frank2,Szita Nicolas1

Affiliation:

1. Department of Biochemical Engineering; University College London; Gordon Street London UK

2. Institute of Analytical Chemistry and Food Chemistry; Graz University of Technology; Graz Austria

3. Member of Merck Group; Sigma-Aldrich; Member of Merck Group; Buchs Switzerland

Funder

Seventh Framework Programme

Biotechnology and Biological Sciences Research Council

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference45 articles.

1. The pH-stat and its use in biochemistry;Jacobsen;Methods Biochem. Anal.,1957

2. Development, operation, and application of the ion-sensitive field-effect transistor as a tool for electrophysiology;Bergveld;IEEE Trans. Biomed. Eng.,1972

3. Field-effect flow control for microfabricated fluidic networks;Schasfoort;Science,1999

4. An integrated silicon sensor with microfluidic chip for monitoring potassium and pH;Sharma;Microfluid. Nanofluid.,2010

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