Observations on conducting whole-cell patch clamping of the hERG cardiac K+channel in pure human serum-Reference-Cited by-同舟云学术

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Observations on conducting whole-cell patch clamping of the hERG cardiac K+channel in pure human serum

Published:2016-08-24 Issue:4 Volume:37 Page:445-453
ISSN:0260-437X
Container-title:Journal of Applied Toxicology
language:en
Short-container-title:J. Appl. Toxicol.

Author:

Kang Jiesheng¹,Luo Yongyi¹,Searles Michelle²,Rampe David³

Affiliation:

1. Departments of Disposition; Safety, and Animal Research Sanofi, Inc.; Waltham Massachusetts USA

2. Departments of Disposition; Safety, and Animal Research Sanofi, Inc.; Framingham Massachusetts USA

3. Departments of Disposition; Safety, and Animal Research Sanofi, Inc.; Bridgewater New Jersey USA

Publisher

Wiley

Subject

Toxicology

Reference45 articles.

1. Synergistic effects of B-estradiol and erythromycin on hERG currents;Ando;J. Membr. Biol.,2011

2. Proton and Zinc effects on HERG currents;Anumonwo;Biophys. J.,1999

3. Total estradiol, free estradiol, sex hormone-binding globulin, and the fraction of estradiol bound to sex hormone-binding globulin in human follicular fluid;Ben-Rafael;J. Clin. Endocrinol. Metab.,1986

4. Pharmacokinetic interaction between domperidone and ketoconazole leads to QT prolongation in healthy volunteers: a randomized, placebo-controlled, double-blind crossover study;Boyce;Br. J. Clin. Pharmacol.,2012

5. Test article concentrations in the hERG assay: Losses through the perfusion, solubility and stability;Brimcombe;J. Pharmacol. Toxicol. Methods,2009

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