Affiliation:
1. Hospital for Special Surgery, Sports Medicine Institute Weill Medical College of Cornell University New York New York USA
2. Department of Orthopaedic Surgery Amsterdam UMC Location University of Amsterdam Amsterdam The Netherlands
3. Amsterdam Movement Sciences, Sports Amsterdam The Netherlands
4. Department of Orthopaedic Surgery Medical Clinic Velsen Velsen‐Noord The Netherlands
Abstract
AbstractPurposeThis study aimed to assess phenotypic variation in the coronal plane of knees with anteromedial osteoarthritis using the functional knee phenotype classification, before and after treatment with medial unicompartmental knee arthroplasty (UKA).MethodsThe study comprised 1000 knees of 835 patients (45% females, 55% males, 90% Caucasian) who underwent medial UKA for anteromedial osteoarthritis. Pre and postoperative alignment was evaluated through the hip‐knee‐ankle angle (HKA), femoral mechanical angle (FMA), and tibial mechanical angle (TMA). Knees were classified according to the functional knee phenotype system which combines limb phenotype (HKA), and femoral and tibial knee phenotypes (FMA and TMA, respectively). Restoration of prearthritic coronal alignment following medial UKA was evaluated by phenotype.ResultsPreoperatively, 76 distinct and 25 relevant (prevalence ≥1%) functional knee phenotypes were identified, of which VARHKA6°VARFMA3°NEUTMA0° was the most common (9.4% of knees). The most prevalent limb phenotype, VARHKA6°, comprised 15 distinct knee phenotypes (FMA and TMA combinations). Postoperatively, 58 distinct and 17 relevant functional knee phenotypes were observed, of which VARHKA3°NEUFMA0°NEUTMA0° had the highest prevalence at 18.3%. Knees with combined tibial and femoral deformities were associated with a lower probability of restoration of prearthritic coronal alignment following medial UKA, compared to knees without extra‐articular deformity, or knees with an isolated tibial or femoral deformity.ConclusionPhenotype analysis using the functional knee phenotype system demonstrated a wide diversity of coronal alignment phenotypes among knees with anteromedial osteoarthritis in a predominantly Caucasian population. Following medial UKA, a reduction from 25 preoperative to 17 postoperative relevant phenotypes was observed. Consideration of phenotypic variation can be of importance when aiming to restore prearthritic coronal alignment during medial UKA.Level of EvidenceLevel III, retrospective cohort study.
Subject
Orthopedics and Sports Medicine,Surgery