Engineering deamidation-susceptible asparagines leads to improved stability to thermal cycling in a lipase

Author:

Bhanuramanand K.1,Ahmad Shoeb1,Rao N. M.1

Affiliation:

1. Centre for Cellular and Molecular Biology (CSIR-CCMB); Hyderabad 500007 India

Funder

UGC (fellowship)

CSIR

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference55 articles.

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2. Why is one Bacillus alpha-amylase more resistant against irreversible thermoinactivation than another?;Tomazic;J Biol Chem,1988

3. Differences in amino acids composition and coupling patterns between mesophilic and thermophilic proteins;Zhou;Amino Acids,2008

4. Comparative proteome analysis of psychrophilic versus mesophilic bacterial species: insights into the molecular basis of cold adaptation of proteins;Metpally;BMC Genom,2009

5. Age-dependent deamidation of lifelong proteins in the human lens;Hains;Invest Ophthalmol Vis Sci,2010

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