Enantioselective capillary electrophoresis for pharmacokinetic analysis of methadone and 2‐ethylidene‐1,5‐dimethyl‐3,3‐diphenylpyrrolidine in equines anesthetized with ketamine and isoflurane-Reference-Cited by-同舟云学术

Enantioselective capillary electrophoresis for pharmacokinetic analysis of methadone and 2‐ethylidene‐1,5‐dimethyl‐3,3‐diphenylpyrrolidine in equines anesthetized with ketamine and isoflurane

Published:2019-03-28 Issue: Volume: Page:
ISSN:0173-0835
Container-title:ELECTROPHORESIS
language:en
Short-container-title:ELECTROPHORESIS

Author:

Theurillat Regula¹,Sandbaumhüter Friederike A.¹,Gittel Claudia²,Larenza Menzies M. Paula³,Braun Christina³,Thormann Wolfgang¹^ORCID

Affiliation:

1. Clinical Pharmacology LaboratoryInstitute for Infectious DiseasesUniversity of Bern Bern Switzerland

2. Department for HorsesUniversity of Leipzig Leipzig Germany

3. Clinical Unit of Anaesthesiology and Perioperative Intensive‐Care MedicineVetmeduni Vienna Vienna Austria

Publisher

Wiley

Subject

Clinical Biochemistry,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/elps.201900044

Reference40 articles.

1. Involvement of Cytochrome P450 3A4 Enzyme in the N-Demethylation of Methadone in Human Liver Microsomes

2. Replacement of (R)-methadone by a double dose of (R, S)-methadone in addicts: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics

3. Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients

4. Methadone—metabolism, pharmacokinetics and interactions

5. Enantiomeric Metabolic Interactions and Stereoselective Human Methadone Metabolism

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