Application of plug-plug technique to ACE experiments for discovery of peptides binding to a larger target protein: A model study of calmodulin-binding fragments selected from a digested mixture of reduced BSA-Reference-Cited by-同舟云学术

Application of plug-plug technique to ACE experiments for discovery of peptides binding to a larger target protein: A model study of calmodulin-binding fragments selected from a digested mixture of reduced BSA

Published:2014-01-13 Issue:6 Volume:35 Page:846-854
ISSN:0173-0835
Container-title:ELECTROPHORESIS
language:en
Short-container-title:ELECTROPHORESIS

Author:

Saito Kazuki¹²³⁴,Nakato Mamiko⁵,Mizuguchi Takaaki⁵,Wada Shinji⁵,Uchimura Hiromasa¹,Kataoka Hiroshi²,Yokoyama Shigeyuki⁴,Hirota Hiroshi⁴,Kiso Yoshiaki⁵

Affiliation:

1. Laboratory of Proteomic Sciences; 21st Century COE Program; Kyoto Pharmaceutical University; Kyoto Japan

2. Department of Integrated Biosciences; Graduate School of Frontier Sciences; University of Tokyo; Kashiwa Chiba Japan

3. Laboratory of Next Generation Drug Development; Graduate School of Frontier Sciences; University of Tokyo; Kashiwa Chiba Japan

4. Protein Research Group; RIKEN Genomic Sciences Center; Tsurumi Yokohama Japan

5. Department of Medicinal Chemistry; Center for Frontier Research in Medicinal Science; Kyoto Pharmaceutical University; Yamashina-ku Kyoto Japan

Funder

21st Century COE Program

National Project on Protein Structural and Functional Analyses

Scientific Research from Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Clinical Biochemistry,Biochemistry,Analytical Chemistry

Reference22 articles.

1. A structure-based strategy for discovery of small ligands binding to functionally unknown proteins: Combination ofin silico screening and surface plasmon resonance measurements

2. NTA-mediated protein capturing strategy in screening experiments for small organic molecules by surface plasmon resonance

3. Protein-protein interactions as a target for drugs in proteomics

4. Computational Drug Design Targeting Protein-Protein Interactions

5. Screening for peptide drugs from the natural repertoire of biodiverse protein folds

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