The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

Author:

Franchi Luigi,Núñez Gabriel

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference27 articles.

1. Aluminium compounds for use in vaccines.;Lindblad;Immunol. Cell Biol.,2004

2. Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: Effect on antigen uptake and antigen presentation.;Mannhalter;Clin. Exp. Immunol.,1985

3. Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants.;Sokolovska;Vaccine,2007

4. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.;Li;J. Immunol.,2007

5. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells.;Kool;J. Exp. Med.,2008

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