TusA (YhhP) and IscS are required for molybdenum cofactor-dependent base-analog detoxification

Author:

Kozmin Stanislav G.1,Stepchenkova Elena I.2,Schaaper Roel M.1

Affiliation:

1. Laboratory of Molecular Genetics; National Institute of Environmental Health Sciences; Research Triangle Park North Carolina 27709

2. Department of Genetics and Biotechnology; St. Petersburg State University, St. Petersburg 199034; and St. Petersburg Branch of Institute of General Genetics; RAS; St. Petersburg 199034 Russia

Funder

National Institute of Environmental Health Sciences

Publisher

Wiley

Subject

Microbiology

Reference47 articles.

1. MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases;Anantharaman;FEMS Microbiol. Lett.,2002

2. Induction of gene mutation in and cell transformation of mammalian cells by modified purines: 2-aminopurine and 6-N-hydroxylaminopurine;Barrett;Proc. Natl. Acad. Sci. USA,1981

3. The Chlamydomonas reinhardtii molybdenum cofactor enzyme crARC has a Zn-dependent activity and protein partners similar to those of its human homologue;Chamizo-Ampudia;Eukaryot. Cell,2011

4. Hepatic microsomal N-hydroxylation of adenine to 6-N-hydroxylaminopurine;Clement;Biochem. Pharmacol.,1990

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