Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor-Reference-Cited by-同舟云学术

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Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor

Published:2022-03-07 Issue:2 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Russell James¹^ORCID,Fanchon Louise¹,Alwaseem Hanan²,Molina Henrik²,O’Donoghue Isabella¹,Bahr Amber³,Stanchina Elisa³,Pillarsetty Nagavarakishore⁴,Humm John L.¹

Affiliation:

1. Department of Medical Physics Memorial Sloan Kettering Cancer Center New York New York USA

2. The Proteomics Resource Center The Rockefeller University New York New York USA

3. Anti‐Tumor Assessment Core Facility Memorial Sloan Kettering Cancer Center New York New York USA

4. Department of Radiology Memorial Sloan Kettering Cancer Center New York New York USA

Funder

Memorial Sloan-Kettering Cancer Center

Leona M. and Harry B. Helmsley Charitable Trust

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.898

Reference26 articles.

1. Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer

2. Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

3. Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

4. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

5. Why HALO 301 Failed and Implications for Treatment of Pancreatic Cancer

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