Loss of Major DNase I Hypersensitive Sites in Duplicatedβ-globinGene Cluster Incompletely SilencesHBBGene Expression-Reference-Cited by-同舟云学术

Loss of Major DNase I Hypersensitive Sites in Duplicatedβ-globinGene Cluster Incompletely SilencesHBBGene Expression

Published:2016-08-25 Issue:11 Volume:37 Page:1153-1156
ISSN:1059-7794
Container-title:Human Mutation
language:en
Short-container-title:Human Mutation

Author:

Reading N. Scott¹²³,Shooter Claire⁴,Song Jihyun²,Miller Robin⁵,Agarwal Archana¹³,Lanikova Lucie²⁶,Clark Barnaby⁴⁷,Thein Swee Lay⁴⁸,Divoky Vladimir⁹¹⁰,Prchal Josef T.¹²³

Affiliation:

1. Institute for Clinical and Experimental Pathology; ARUP Laboratories; Salt Lake City Utah

2. Division of Hematology, Department of Internal Medicine, School of Medicine; University of Utah; Salt Lake City Utah

3. Department of Pathology, School of Medicine; University of Utah; Salt Lake City Utah

4. Molecular Haematology, Division of Cancer Studies; King's College London Faculty of Life Sciences & Medicine; London UK

5. Center for Cancer and Blood Disorders; Nemours/El Dupont Hospital for Children; Wilmington Delaware

6. Department of Cell and Developmental Biology, Institute of Molecular Genetics; Academy of Sciences of the Czech Republic; Prague Czech Republic

7. Department of Molecular Pathology; Viapath at King's College Hospital NHS Foundation Trust; London UK

8. National Heart, Lung and Blood Institute, Sickle Cell Branch; National Institutes of Health; Bethesda Maryland

9. Department of Biology, Faculty of Medicine and Dentistry; Palacky University; Olomouc Czech Republic

10. Department of Biology, Faculty of Medicine; Masaryk University; Brno Czech Republic

Funder

Czech Republic Program KONTAKT II

SLT - King's College Hospital Charity

Publisher

Wiley

Subject

Genetics (clinical),Genetics

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4. Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription;Bender;Blood,2006

5. Functional and mechanistic diversity of distal transcription enhancers;Bulger;Cell,2011

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