Design, Synthesis and Evaluation of 2,4‐Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors-Reference-Cited by-同舟云学术

Design, Synthesis and Evaluation of 2,4‐Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors

Published:2020-08-26 Issue:19 Volume:15 Page:1802-1812
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Herrera‐Vázquez Frida S.¹,Matadamas‐Martínez Félix¹²,Aguayo‐Ortiz Rodrigo³⁴,Dominguez Laura³,Ramírez‐Apan Teresa⁵,Yépez‐Mulia Lilián²,Hernández‐Luis Francisco¹^ORCID

Affiliation:

1. Departamento de Farmacia Universidad Nacional Autónoma de México Mexico City 04510 Mexico

2. Unidad Médica de Alta Especialidad-Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social Mexico City 06720 Mexico

3. Departamento de Fisicoquímica Universidad Nacional Autónoma de México Mexico City 04510 Mexico

4. Department of Internal Medicine Division of Cardiovascular Medicine University of Michigan Ann Arbor MI 48109 USA

5. Instituto de Química Universidad Nacional Autónoma de México Mexico City 04510 Mexico

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000185

Reference56 articles.

1. The chemical complexity of cellular microtubules: Tubulin post-translational modification enzymes and their roles in tuning microtubule functions

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5. Microtubules as antifungal and antiparasitic drug targets

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