Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class-Reference-Cited by-同舟云学术

Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class

Published:2022-01-11 Issue: Volume: Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Diamanti Eleonora¹²,Hamed Mostafa M.¹,Lacour Antoine¹³,Bravo Patricia⁴⁵,Illarionov Boris⁶,Fischer Markus⁶,Rottmann Matthias⁴⁵,Witschel Matthias⁷,Hirsch Anna K. H.¹²³^ORCID

Affiliation:

1. Helmholtz Institute for Pharmaceutical Research (HIPS) Helmholtz Centre for Infection Research (HZI) Saarland University Campus E8.1 66123 Saarbrücken Germany

2. Helmholtz International Lab for Anti-Infectives Saarland University Campus E8.1 66123 Saarbrücken Germany

3. Department of Pharmacy Saarland University Campus E8.1 66123 Saarbrücken Germany

4. Swiss Tropical and Public Health Institute Socinstrasse 57 4002 Basel Switzerland

5. Universität Basel Petersplatz 1 4003 Basel Switzerland

6. Hamburg School of Food Science University of Hamburg Grindelallee 117 20146 Hamburg Germany

7. BASF-SE Carl-Bosch-Strasse 38 67056 Ludwigshafen Germany

Funder

European Research Council

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100679

Reference31 articles.

2. The function of terpene natural products in the natural world

3. Isoprenoid biosynthesis in bacterial pathogens

4. Development of Inhibitors of the 2C-Methyl-d-erythritol 4-Phosphate (MEP) Pathway Enzymes as Potential Anti-Infective Agents

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