GluN2A‐Selective NMDA Receptor Antagonists: Mimicking the U‐Shaped Bioactive Conformation of TCN‐201 by a [2.2]Paracyclophane System-Reference-Cited by-同舟云学术

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GluN2A‐Selective NMDA Receptor Antagonists: Mimicking the U‐Shaped Bioactive Conformation of TCN‐201 by a [2.2]Paracyclophane System

Published:2022-10-13 Issue:21 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Steigerwald Ruben¹²,Chou Tsung‐Han³,Furukawa Hiro³,Wünsch Bernhard¹²^ORCID

Affiliation:

1. Chemical biology of ion channels (Chembion) Westfälische Wilhelms-Universität Münster Corrensstraße 48 48149 Münster Germany

2. Institut für Pharmazeutische und Medizinische Chemie Westfälische Wilhelms-Universität Münster Corrensstraße 48 48149 Münster Germany

3. W.M. Keck Structural Biology Laboratory Cold Spring Harbor Laboratory New York NY 11724 USA

Funder

Deutsche Forschungsgemeinschaft

National Institutes of Health

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200484

Reference31 articles.

1. Glutamate Receptor Ion Channels: Structure, Regulation, and Function

2. Crystal structure of a heterotetrameric NMDA receptor ion channel

3. NMDA receptor subtypes: Structure, function and therapeutics

4. GluN1 splice variant control of GluN1/GluN2D NMDA receptors

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of GluN2A subtype-selective N-methyl-d-aspartate (NMDA) receptor ligands;Acta Pharmaceutica Sinica B;2024-05

2. GluN2A and GluN2B N-Methyl-D-Aspartate Receptor (NMDARs) Subunits: Their Roles and Therapeutic Antagonists in Neurological Diseases;Pharmaceuticals;2023-10-30

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