Structure‐Activity Studies of Truncated Latrunculin Analogues with Antimalarial Activity

Author:

Varghese Swapna12,Rahmani Raphaël2,Drew Damien R.3,Beeson James G.34,Baum Jake56,Smith Brian J.1,Baell Jonathan B.278ORCID

Affiliation:

1. La Trobe Institute for Molecular Science La Trobe University Melbourne Victoria 3086 Australia

2. Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences Monash University Parkville Victoria 3052 Australia

3. Burnet Institute 85 Commercial Road Melbourne Victoria 3004 Australia

4. Central Clinical School and Department of Microbiology Monash University Melbourne Victoria 3004 Australia

5. Walter and Eliza Hall Institute 1G Royal Parade Parkville Victoria 3052 Australia

6. Department of Life Sciences Imperial College London South Kensington SW7 2AZ UK

7. Australian Translational Medicinal Chemistry Facility (ATMCF) Monash University Parkville, Victoria 3052 Australia

8. ARC Centre for Fragment-Based Design Monash University Parkville Victoria 3052 Australia

Funder

Australian Government

Wellcome Trust

National Health and Medical Research Council

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference33 articles.

1. Malaria fact sheet.World Health Organizationaccess date 1 June 2019 https://www.who.int/en/news-room/fact-sheets/detail/malaria.

2. B. Hanboonkunupakarn N. J. White The threat of antimalarial drug resistance.Tropical Diseases Travel Medicine and Vaccines2016 2 10.

3. World Malaria Report.https://apps.who.int/iris/bitstream/handle/10665/275867/9789241565653-eng.pdf?ua=1access date 1 June 2019.

4. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

5. Malaria Parasites in the Asymptomatic: Looking for the Hay in the Haystack

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