Synthesis and in Vitro Evaluation of Novel 5‐Nitroindole Derivatives as c‐Myc G‐Quadruplex Binders with Anticancer Activity-Reference-Cited by-同舟云学术

Synthesis and in Vitro Evaluation of Novel 5‐Nitroindole Derivatives as c‐Myc G‐Quadruplex Binders with Anticancer Activity

Published:2021-03-22 Issue:10 Volume:16 Page:1667-1679
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Nimbarte Vijaykumar D.¹^ORCID,Wirmer‐Bartoschek Julia¹^ORCID,Gande Santosh L.¹²,Alshamleh Islam¹^ORCID,Seibert Marcel³,Nasiri Hamid Reza¹,Schnütgen Frank²³⁴^ORCID,Serve Hubert²³⁴^ORCID,Schwalbe Harald¹²⁴^ORCID

Affiliation:

1. Institute for Organic Chemistry and Chemical Biology Center for Biomolecular Magnetic Resonance (BMRZ) Goethe University Frankfurt Max-von-Laue-Straße 7 60438 Frankfurt am Main Germany

2. German Cancer Research Center and German Cancer Consortium Im Neuenheimer Feld 280 69120 Heidelberg Germany

3. Department of Medicine 2 Hematology/Oncology University Hospital Frankfurt Goethe University Theodor-Stern-Kai 7 60596 Frankfurt am Main Germany

4. Frankfurt Cancer Institute (FCI) Theodor-Stern-Kai 7 60596 Frankfurt am Main Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000835

Reference48 articles.

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3. Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

4. High-throughput sequencing of DNA G-quadruplex structures in the human genome

5. G-quadruplex structures mark human regulatory chromatin

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