Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)-Reference-Cited by-同舟云学术

Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)

Published:2021-03-16 Issue:8 Volume:16 Page:1257-1267
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Voos Katrin¹^ORCID,Schönauer Esther²^ORCID,Alhayek Alaa³⁴^ORCID,Haupenthal Jörg³^ORCID,Andreas Anastasia⁵⁴,Müller Rolf⁵⁴^ORCID,Hartmann Rolf W.³⁴^ORCID,Brandstetter Hans²^ORCID,Hirsch Anna K. H.³⁴^ORCID,Ducho Christian¹^ORCID

Affiliation:

1. Department of Pharmacy Pharmaceutical and Medicinal Chemistry Saarland University Campus C2 3 66123 Saarbrücken Germany

2. Department of Biosciences and Christian Doppler Laboratory for Innovative Tools for Biosimilar Characterization Division of Structural Biology University of Salzburg Billrothstrasse 11 5020 Salzburg Austria

3. Department of Drug Design and Optimization Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI) Campus E8 1 66123 Saarbrücken Germany

4. Department of Pharmacy Saarland University Campus E8 1 66123 Saarbrücken Germany

5. Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI) Campus E8 1 66123 Saarbrücken Germany

Funder

Austrian Science Fund

European Research Council

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000994

Reference74 articles.

2. J. O'Neill Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations UK Government & Wellcome Trust London 2014;

3. Drug-Resistant Infections: A Threat to Our Economic Future The World Bank Washington DC 2017.

4. No Time to Wait: Securing the Future from Drug-Resistant Infections The World Health Organization 2019.

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