Identification of the FDA‐Approved Drug Pyrvinium as a Small‐Molecule Inhibitor of the PD‐1/PD‐L1 Interaction-Reference-Cited by-同舟云学术

Identification of the FDA‐Approved Drug Pyrvinium as a Small‐Molecule Inhibitor of the PD‐1/PD‐L1 Interaction

Published:2021-06-29 Issue:18 Volume:16 Page:2769-2774
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Fattakhova Elena¹,Hofer Jeremy²,DiFlumeri Juliette¹,Cobb Madison¹,Dando Timothy¹,Romisher Zachary¹,Wellington Justin¹,Oravic Michael³,Radnoff Madison¹,Patil Sachin P.⁴^ORCID

Affiliation:

1. Department of Chemical Engineering Widener University Chester PA 19013 USA

2. Department of Computer Science Widener University Chester PA 19013 USA

3. Department of Biomedical Engineering Widener University Chester PA 19013 USA

4. NanoBio Laboratory Widener University Chester PA 19013 USA

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100264

Reference29 articles.

1. Targeting Programmed Cell Death -1 (PD-1) and Ligand (PD-L1): A new era in cancer active immunotherapy

2. Cancer immunologists scoop medicine Nobel prize

3. The Diverse Function of PD-1/PD-L Pathway Beyond Cancer

4. PD-L1 Distribution and Perspective for Cancer Immunotherapy—Blockade, Knockdown, or Inhibition

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