Synthesis of Fluorinated Imidazole[4,5 f ][1,10]phenanthroline Derivatives as Potential Inhibitors of Liver Cancer Cell Proliferation by Inducing Apoptosis via DNA Damage-Reference-Cited by-同舟云学术

Synthesis of Fluorinated Imidazole[4,5 f ][1,10]phenanthroline Derivatives as Potential Inhibitors of Liver Cancer Cell Proliferation by Inducing Apoptosis via DNA Damage

Published:2021-11-24 Issue: Volume: Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Bai Ming‐Jun¹,Liu Ning‐Zhi²,Zhou Yu‐Ling³,Liu Jie³,Zou Jun²,Tan Wei‐Jun⁴,Huang Xiao‐Ting²,Mei Wen‐Jie²⁵^ORCID

Affiliation:

1. Department of Interventional Radiology The Third Affiliated Hospital of Sun Yat-sen University Guangzhou 510430 China

2. School of Pharmacy Guangdong Pharmaceutical University Guangzhou 510006 China

3. Department of Pharmacy The Third Affiliated Hospital of Sun Yat-sen University Guangzhou 510430 China

4. School of Food Guangdong Pharmaceutical University Guangzhou 510006 China

5. Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-Medicine Imaging Guangzhou 510006 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100537

Reference39 articles.

1. Synthesis of [14C]imidazole ring labeled metiamide, cimetidine and impromidine

2. Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

3. Recent advances of imidazole-containing derivatives as anti-tubercular agents

4. An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO2(NO3)2·6H2O under heterogeneous conditions

5. Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions

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