Design, Synthesis, and in vitro Evaluation of Tubulin‐Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block-Reference-Cited by-同舟云学术

Design, Synthesis, and in vitro Evaluation of Tubulin‐Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block

Published:2021-07-29 Issue:19 Volume:16 Page:3003-3016
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Guerra Walter D.¹^ORCID,Lucena‐Agell Daniel²^ORCID,Hortigüela Rafael²^ORCID,Rossi Roberto A.¹^ORCID,Fernando Díaz J.²^ORCID,Padrón José M.³^ORCID,Barolo Silvia M.¹^ORCID

Affiliation:

1. Instituto de Investigaciones en Físico Química de Córdoba Departamento de Química Orgánica Facultad de Ciencias Químicas Universidad Nacional de Córdoba X5000HUA Córdoba Argentina

2. Centro de Investigaciones Biológicas Margarita Salas (CIB-MS, CSIC) Ramiro de Maeztu 9 28040 Madrid Spain

3. BioLab Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG) Universidad de La Laguna C/Astrofísico Francisco Sánchez 2 38206 La Laguna Spain

Funder

European Commission

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100383

Reference84 articles.

1. Cancer statistics, 2020

2. Envisioning the future of early anticancer drug development

3. Tubulin inhibitors: a patent review