Design, Synthesis, Structure‐Activity Relationship and Docking Studies of Novel Functionalized Arylvinyl‐1,2,4‐Trioxanes as Potent Antiplasmodial as well as Anticancer Agents

Author:

Tiwari Mohit K.1,Coghi Paolo2,Agrawal Prakhar3,Shyamlal Bharti Rajesh K.1,Jun Yang Li4,Yadav Lalit1,Peng Yuzhong2,Sharma Richa1,Yadav Dharmendra K.5,Sahal Dinkar3,Kam Wai Wong Vincent4,Chaudhary Sandeep1ORCID

Affiliation:

1. Laboratory of Organic and Medicinal ChemistryDepartment of ChemistryMalaviya National Institute of Technology Jawaharlal Nehru Marg Jaipur 302017 India

2. School of PharmacyMacau University of Science and Technology Avenida wai long Taipa Macau China

3. Malaria Drug Discovery LaboratoryInternational Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Marg 110 067 New Delhi India

4. State Key Laboratory of Quality Research in Chinese MedicineMacau University of Science and Technology Avenida Wai Long Taipa Macau China

5. College of PharmacyGachon University of Medicine and Science Hambakmoeiro 191, Yeonsu-gu Incheon city 406-799 South Korea

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference74 articles.

1. World Malaria Report: 2018. WHO Geneva 2018 https://apps.who.int.

2. The Plasmodium falciparum-infected red blood cell

3. Open heart surgery in sub-Saharan Africa: challenges and promise

4. “Biography of Youyou Tu” The Nobel Foundation. [Accessed Nov-2019].

5.  

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