Nanoporous Gold Catalyst for the Oxidative N‐Dealkylation of Drug Molecules: A Method for Synthesis of N‐Dealkylated Metabolites-Reference-Cited by-同舟云学术

Nanoporous Gold Catalyst for the Oxidative N‐Dealkylation of Drug Molecules: A Method for Synthesis of N‐Dealkylated Metabolites

Published:2022-04-05 Issue:11 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Alipour Najmi Ali¹,Jafariyeh‐Yazdi Elchin²,Hadian Mojgan³,Hermans Jos¹,Bischoff Rainer¹,Yue Jun²,Dömling Alexander³,Wittstock Arne⁴,Permentier Hjalmar P.¹^ORCID

Affiliation:

1. Department of Analytical Biochemistry Groningen Research Institute of Pharmacy University of Groningen A Deusinglaan 1 9713 AV Groningen The Netherlands

2. Department of Chemical Engineering Engineering and Technology Institute Groningen University of Groningen 9747 AG Groningen The Netherlands

3. Department of Drug Design University of Groningen A Deusinglaan 1 9713 AV Groningen The Netherlands

4. Institute of Applied and Physical Chemistry and Center for Environmental Research and Sustainable Technology University Bremen Leobener Str. 6 28359 Bremen Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200040

Reference46 articles.

1. Mapping human microbiome drug metabolism by gut bacteria and their genes

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4. X. Zhuo N. Zheng Drug Metabolism | Metabolite Isolation and Identification Elsevier Inc. 2019.

5. Selective Synthesis of the Human Drug Metabolite 5′-Hydroxypropranolol by an Evolved Self-Sufficient Peroxygenase

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