Systematic Assessment of Fragment Identification for Multitarget Drug Design-Reference-Cited by-同舟云学术

Systematic Assessment of Fragment Identification for Multitarget Drug Design

Published:2021-02-04 Issue:7 Volume:16 Page:1088-1092
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Brunst Steffen¹,Kramer Jan S.¹,Kilu Whitney¹,Heering Jan²,Pollinger Julius¹,Hiesinger Kerstin¹,George Sven¹,Steinhilber Dieter¹²,Merk Daniel¹,Proschak Ewgenij¹²^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry Goethe University Max-von-Laue Str. 9 60438 Frankfurt Germany

2. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Theodor-Stern-Kai 7 60596 Frankfurt Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000858

Reference33 articles.

1. Harnessing Polypharmacology with Medicinal Chemistry

2. Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds

3. Designed Multiple Ligands. An Emerging Drug Discovery Paradigm

4. The Physicochemical Challenges of Designing Multiple Ligands

5. Fragments, network biology and designing multiple ligands

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