Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline‐Based κ‐Opioid Receptor (KOR) Agonists Designed for PET Studies-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline‐Based κ‐Opioid Receptor (KOR) Agonists Designed for PET Studies

Published:2020-09 Issue:19 Volume:15 Page:1834-1853
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Tangherlini Giovanni¹²,Börgel Frederik¹,Schepmann Dirk¹,Slocum Samuel³,Che Tao⁴,Wagner Stefan⁵,Schwegmann Katrin⁶,Hermann Sven⁶,Mykicki Nadine⁷,Loser Karin²⁷⁸,Wünsch Bernhard¹²^ORCID

Affiliation:

1. Institut für Pharmazeutische und Medizinische Chemie Universität Münster Corrensstraße 48 48149 Münster Germany

2. Cells-in-Motion Cluster of Excellence (EXC 1003-CiM) Westfälische Wilhelms-Universität Münster 48149 Münster Germany

3. Department of Pharmacology University of North Carolina at Chapel Hill School of Medicine Chapel Hill NC 27599 USA

4. Department of Anesthesiology Washington University School of Medicine 660 S. Euclid Ave. St. Louis MO 63110 USA

5. Department of Nuclear Medicine University Hospital Münster Albert-Schweitzer-Campus 1, Building A1 48149 Münster Germany

6. European Institute for Molecular Imaging (EIMI) University of Münster Waldeyerstraße 15 48149 Münster Germany

7. Department of Dermatology University of Münster von-Esmarch-Str. 58 48149 Münster Germany

8. CRC1009 Breaking Barriers and CRC-TR 128 Multiple Sclerosis University of Münster von-Esmarch-Str. 58 48149 Münster Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000502

Reference57 articles.

1. Mu Opioids and Their Receptors: Evolution of a Concept

2. Mu opioid receptors in pain management

3. Delta and Kappa Opioid Receptors as Suitable Drug Targets for Pain

4. The Therapeutic Potential of κ-Opioids for Treatment of Pain and Addiction

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