Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings

Author:

Hale Emma A.1,Ryan Hannah M.1,McOsker Alexandra M.1,Funk Cody M.1,Green Lauren C.1,Mazur Lauren E.1,Uthappa Diya M.1,Flood Brian M.1,Young Douglas D.1ORCID,Hinkle Robert J.1ORCID

Affiliation:

1. Department of Chemistry William & Mary PO Box 8795 Williamsburg, VA 23187 USA

Funder

Camille and Henry Dreyfus Foundation

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference46 articles.

1. For a 2019 report on antibiotic resistance threats entitled: Antibiotic Resistance Threats in the United States 2019. Atlanta GA: U. S. Department of Health and Human Services CDC; 2019 see: https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf DOI: https://stacks.cdc.gov/view/cdc/82532.

2. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

3. Recent reviews:

4. Polyacetylenes in herbal medicine: A comprehensive review of its occurrence, pharmacology, toxicology, and pharmacokinetics (2014–2021)

5. Polyacetylene Glycosides: Isolation, Biological Activities and Synthesis

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