Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach-Reference-Cited by-同舟云学术

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Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach

Published:2021-03-08 Issue:10 Volume:16 Page:1605-1608
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Saha Debasmita¹,Ryan Katie Rose²^ORCID,Lakkaniga Naga Rajiv¹³,Smith Erica Lane¹,Frett Brendan¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences College of Pharmacy University of Arkansas for Medical Sciences Little Rock AR 72205 USA

2. Department of Biochemistry and Molecular Biology College of Medicine University of Arkansas for Medical Sciences Little Rock AR 72205 USA

3. SmartBio Labs 126, Rajamannar Salai, K. K. nagar, Tamilnadu Chennai 600078 India.

Funder

American Thyroid Association

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100013

Reference21 articles.

1. Expression of theRET proto-oncogene in human Embryos

2. RET tyrosine kinase signaling in development and cancer

3. Minireview: RET: Normal and Abnormal Functions

4. REToma: a cancer subtype with a shared driver oncogene

5. KIF5B-RET fusions in lung adenocarcinoma

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enhancer‐activated RET confers protection against oxidative stress to KMT2A‐rearranged acute myeloid leukemia;Cancer Science;2024-01-16

2. Fragment-to-Lead Medicinal Chemistry Publications in 2021;Journal of Medicinal Chemistry;2023-01-09

3. Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development;Journal of Medicinal Chemistry;2021-08-17

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