A Small Molecule with Bridged Carbonyl and Tri‐fluoro‐aceto‐phenone Groups Impedes Microtubule Dynamics and Subsequently Triggers Cancer Cell Apoptosis-Reference-Cited by-同舟云学术

A Small Molecule with Bridged Carbonyl and Tri‐fluoro‐aceto‐phenone Groups Impedes Microtubule Dynamics and Subsequently Triggers Cancer Cell Apoptosis

Published:2021-06-19 Issue:17 Volume:16 Page:2703-2714
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Mohapatra Saswat¹,Gupta Varsha¹,Mondal Prasenjit¹,Chatterjee Shreyam²,Bhunia Debmalya¹,Ghosh Surajit³¹^ORCID

Affiliation:

1. Department of Organic and Medicinal Chemistry Division CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullick Road Jadavpur, Kolkata, West Bengal 700032 India

2. The Institute of Scientific and Industrial Research Osaka University 8-1, Mihogaoka Ibaraki, Osaka 567-0047 Japan

3. Department of Bioscience & Bioengineering Indian Institute of Technology Jodhpur NH 62, Surpura Bypass Road Karwar, Rajasthan 342037 India

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100192

Reference52 articles.

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2. Refined structure of αβ-tubulin at 3.5 Å resolution 1 1Edited by I. A. Wilson

3. Tubulin structure: insights into microtubule properties and functions

4. Microtubule structure and dynamics

5. Unraveling cell division mechanisms with small-molecule inhibitors

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