Design and Synthesis of Fsp3‐Enriched Spirocyclic‐Based Biological Screening Compound Arrays via DOS Strategies and Their NNMT Inhibition Profiling-Reference-Cited by-同舟云学术

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Design and Synthesis of Fsp3‐Enriched Spirocyclic‐Based Biological Screening Compound Arrays via DOS Strategies and Their NNMT Inhibition Profiling

Published:2022-10-27 Issue:24 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Iusupov Ildar R.¹,Lukyanenko Evgeny R.¹,Altieri Andrea¹²,Kurkin Alexander V.¹^ORCID

Affiliation:

1. Department of Chemistry Lomonosov Moscow State University 1/3 Leninsky Gory Moscow 119991 Russia

2. EDASA Scientific Srls Via Stingi, 3 66050 San Salvo Italy

Funder

Russian Foundation for Basic Research

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200394

Reference53 articles.

1. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

2. Time-Related Differences in the Physical Property Profiles of Oral Drugs

3. A drug-likeness toolbox facilitates ADMET study in drug discovery

4. The Properties of Known Drugs. 1. Molecular Frameworks

5. Evolution of commercially available compounds for HTS

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phenotypic assessment of antiviral activity for spiro‐annulated oxepanes and azepenes;Chemical Biology & Drug Design;2024-05

2. Stereoselective synthesis of spirocyclic derivatives of functionalized 2,3,4,7-tetrahydro-1H-azepines;Mendeleev Communications;2024-03

3. Synthesis of Substituted Pyrrole Derivatives Based on 8-Azaspiro[5.6]dodec-10-ene Scaffold;Molbank;2024-01-25

4. (1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol Dihydrochloride;Molbank;2022-11-15

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