6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects**-Reference-Cited by-同舟云学术

6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects**

Published:2022-02-10 Issue:7 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Akins Nicholas S.¹,Mishra Nisha¹,Harris Hannah M.²,Dudhipala Narendar³,Kim Seong Jong⁴,Keasling Adam W.¹,Majumdar Soumyajit²³,Zjawiony Jordan K.¹²,Paris Jason J.¹²,Ashpole Nicole M.¹²,Le Hoang V.¹²^ORCID

Affiliation:

1. Department of BioMolecular Sciences School of Pharmacy University of Mississippi, University MS 38677 USA

2. Research Institute of Pharmaceutical Sciences School of Pharmacy University of Mississippi University MS 38677 USA

3. Department of Pharmaceutics and Drug Delivery School of Pharmacy University of Mississippi University MS 38677 USA

4. Natural Products Utilization Research Unit United States Department of Agriculture Agricultural Research Service University MS 38677 USA

Funder

National Institute of General Medical Sciences

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100684

Reference26 articles.

1. Chronic Pain and Mental Health Disorders

2. Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults — United States, 2016

3. Designing Safer Analgesics via μ-Opioid Receptor Pathways

4. Rates of opioid misuse, abuse, and addiction in chronic pain

5. Novel Orally Available Salvinorin A Analog PR-38 Inhibits Gastrointestinal Motility and Reduces Abdominal Pain in Mouse Models Mimicking Irritable Bowel Syndrome

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3. Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-Based Antagonists and Kappa Opioid Receptor;ACS Chemical Neuroscience;2023-02-16

4. A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse;European Journal of Medicinal Chemistry;2022-12

5. Fimbristylis aestivalis Vahl: a potential source of cyclooxygenase-2 (COX-2) inhibitors;Inflammopharmacology;2022-09-03