Small‐Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection-Reference-Cited by-同舟云学术

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Small‐Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection

Published:2020-12-03 Issue:2 Volume:16 Page:377-387
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Xu David¹²^ORCID,Bum‐Erdene Khuchtumur¹,Leth Julie M.³⁴,Ghozayel Mona K.¹,Ploug Michael³⁴^ORCID,Meroueh Samy O.¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology Indiana University School of Medicine Indianapolis IN 46202 USA

2. Center for Computational Biology and Bioinformatics Indiana University School of Medicine Indianapolis IN 46202 USA

3. Finsen Laboratory Rigshospitalet 2200 Copenhagen N Denmark

4. Biotech Research and Innovation Centre University of Copenhagen 2200 Copenhagen N Denmark

Funder

American Cancer Society

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000558

Reference69 articles.

1. Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

2. Evolution and Medical Significance of LU Domain−Containing Proteins

3. Systematic Mutational Analysis of the Receptor-Binding Region of the Human Urokinase-Type Plasminogen Activator

4. Mapping of the Vitronectin-binding Site on the Urokinase Receptor

5. uPAR-induced cell adhesion and migration: vitronectin provides the key

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeted imaging of uPAR expression in vivo with cyclic AE105 variants;Scientific Reports;2023-10-11

2. Structural Dynamics-Driven Discovery of Anticancer and Antimetastatic Effects of Diltiazem and Glibenclamide Targeting Urokinase Receptor;Journal of Medicinal Chemistry;2023-02-28

3. Exogenous Urokinase Inhibits Proteasomal Degradation of Its Cognate Urokinase Plasminogen Activator Receptor;Frontiers in Pharmacology;2022-08-12

4. MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism;Frontiers in Pharmacology;2022-04-28

5. Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer;Journal of Translational Medicine;2022-03-18

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