Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs-Reference-Cited by-同舟云学术

Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs

Published:2022-04-29 Issue:17 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Yoshida Yuki¹,Zheng Ti¹,Tanabe Wataru¹,Tomoike Fumiaki²³^ORCID,Hashiya Fumitaka²,Suzuki Tetsuro⁴^ORCID,Hirota Shuto⁵⁶,Saiki Yuriko⁵⁶⁷^ORCID,Horii Akira⁵^ORCID,Hirayama Akiyoshi⁸^ORCID,Soga Tomoyosi⁸^ORCID,Kimura Yasuaki¹^ORCID,Abe Hiroshi¹⁹¹⁰^ORCID

Affiliation:

1. Graduate School of Science Department of Chemistry Nagoya University Furo-cho, Chikusa-ku Nagoya Aichi 464-8602 Japan

2. Research Center for Material Science Nagoya University Furo-cho, Chikusa-ku Nagoya Aichi 464-8602 Japan

3. Department of Life Science Gakushuin University 15-1 Mejiro, Toshima-ku Tokyo 171-8588 Japan

4. Department of Virology and Parasitology Hamamatsu University School of Medicine 1-20-1 Handayama, Higashi-ku Hamamatsu Shizuoka 431-3192 Japan

5. Department of Molecular Pathology School of Medicine Tohoku University Seiryo-machi, Aoba-ku Sendai Miyagi 980-8575 Japan

6. Department of Investigative Pathology School of Medicine Tohoku University Seiryo-machi, Aoba-ku Sendai Miyagi 980-8575 Japan

7. Office of Medical Education School of Medicine Tohoku University Seiryo-machi, Aoba-ku Sendai Miyagi 980-8575 Japan

8. Institute for Advanced Biosciences Keio University Kakuganji 246-2 Mizukami, Tsuruoka Yamagata 997-0052 Japan

9. CREST Japan Science and Technology Agency 7 Gobancho, Chiyoda-ku Tokyo 102-0076 Japan

10. Institute for Glyco-core Research (iGCORE) Tokai National Higher Education and Research System Furo-cho, Chikusa-ku Nagoya Aichi 464-8601 Japan

Funder

Japan Agency for Medical Research and Development

Takeda Science Foundation

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200188

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