Synthesis and Antitrypanosomal Activity of 1,4‐Disubstituted Triazole Compounds Based on a 2‐Nitroimidazole Scaffold: a Structure‐Activity Relationship Study-Reference-Cited by-同舟云学术

Synthesis and Antitrypanosomal Activity of 1,4‐Disubstituted Triazole Compounds Based on a 2‐Nitroimidazole Scaffold: a Structure‐Activity Relationship Study

Published:2020-09-15 Issue:21 Volume:15 Page:2019-2028
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Assunção Elvis L. F.¹,Carvalho Diego B.¹,das Neves Amarith R.¹,Kawasoko Shiguemotto Cristiane Y.¹,Portapilla Gisele B.²,Albuquerque Sergio²,Baroni Adriano C. M.¹^ORCID

Affiliation:

1. Laboratório de Síntese e Química Medicinal (LASQUIM) Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição Universidade Federal do Mato Grosso do Sul – UFMS Campo Grande Mato Grosso do Sul CEP 79051-470 Brazil

2. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo Ribeirão Preto São Paulo,CEP 14040-900 Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000460

Reference65 articles.

1. WHO “Chagas Disease ” can be found under https://www.who.int/health-topics/chagas-disease#tab=tab_1 2020.

2. DNDi “Drugs for Neglected Diseases Initiative (DNDi). Plataforma Chagas. ” can be found under https://www.dndi.org/diseases-projects/portfolio/fexinidazole 2020.

3. Chagas disease

4. Socioeconomic aspects of neglected tropical diseases

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