Discovery of a Lead Brain‐Penetrating Gonadotropin‐Releasing Hormone Receptor Antagonist with Saturable Binding in Brain-Reference-Cited by-同舟云学术

Discovery of a Lead Brain‐Penetrating Gonadotropin‐Releasing Hormone Receptor Antagonist with Saturable Binding in Brain

Published:2020-08-10 Issue:17 Volume:15 Page:1624-1628
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Bekker Roberto B. W.¹,Fjellaksel Richard²³⁴,Hjornevik Trine⁵,Nuruddin Syed⁶,Rafique Waqas¹,Hansen Jørn H.⁴,Sundset Rune²³,Haraldsen Ira H.⁷,Riss Patrick J.¹⁶⁷

Affiliation:

1. Department of ChemistryUniversity of Oslo Sem Sælands vei, 26 0371 Oslo Norway

2. Department of Clinical MedicineUiT The Arctic University of Norway Hansine Hansens veg 18 9019 Tromsø Norway

3. PET Imaging CenterUniversity Hospital of North Norway Sykehusvegen 38 9019 Tromsø Norway

4. Department of ChemistryUiT – The Arctic University of Norway Hansine Hansens veg 18 9019 Tromsø Norway

5. Department of Diagnostic PhysicsOslo University Hospital Sognsvannsveien 20 0372 Oslo Norway

6. Norwegian Medical Cyclotron AS, Rikshospitalet Sognsvannsveien 20 Oslo Norway

7. Clinical NeurosciencesOslo University Hospital-Ulleval Kirkeveien 166, post code? Oslo Norway

Funder

Norges Forskningsråd

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000256

Reference23 articles.

1. Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone

2. Testosterone Surge: Rationale for Gonadotropin-Releasing Hormone Blockers?

3. Ganirelix acetate causes a rapid reduction in estradiol levels without adversely affecting oocyte maturation in women pretreated with leuprolide acetate who are at risk of ovarian hyperstimulation syndrome*

4. The Gonadotropin Connection in Alzheimer's Disease

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The historical progression of positron emission tomography research in neuroendocrinology;Frontiers in Neuroendocrinology;2023-07