Discovery of a Histidine‐Based Scaffold as an Inhibitor of Gut Microbial Choline Trimethylamine‐Lyase-Reference-Cited by-同舟云学术

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Discovery of a Histidine‐Based Scaffold as an Inhibitor of Gut Microbial Choline Trimethylamine‐Lyase

Published:2020-09-10 Issue:23 Volume:15 Page:2273-2279
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Gabr Moustafa¹^ORCID,Świderek Katarzyna²

Affiliation:

1. Department of Radiology School of Medicine Stanford University Stanford CA 94305 USA

2. Departament de Química Física i Analítica Universitat Jaume I 12071 Castellón Spain

Funder

Generalitat Valenciana

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000571

Reference50 articles.

1. Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ

2. Interactions Between Food and Gut Microbiota: Impact on Human Health

3. Gut Microbiota in Cardiovascular Health and Disease

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1. Dysfunction of cecal microbiota and CutC activity in mice mediating diarrhea with kidney-yang deficiency syndrome;Frontiers in Microbiology;2024-03-04

2. Targeting the human gut microbiome with small-molecule inhibitors;Nature Reviews Chemistry;2023-04-18

3. Gut Failure: A Review of the Pathophysiology and Therapeutic Potentials in the Gut–Heart Axis;Journal of Clinical Medicine;2023-03-29

4. Gut Microbial-Derived Metabolites as Immune Modulators of T Helper 17 and Regulatory T Cells;International Journal of Molecular Sciences;2023-01-16

5. First-in-class small molecule inhibitors of ICOS/ICOSL interaction as a novel class of immunomodulators;RSC Medicinal Chemistry;2023

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