Synthesis and Initial Characterization of a Selective, Pseudo‐irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer-Reference-Cited by-同舟云学术

Synthesis and Initial Characterization of a Selective, Pseudo‐irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer

Published:2021-03 Issue:9 Volume:16 Page:1427-1437
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Gentzsch Christian¹,Hoffmann Matthias¹,Ohshima Yasuhiro²³,Nose Naoko⁴,Chen Xinyu⁵²³,Higuchi Takahiro²³⁴,Decker Michael¹^ORCID

Affiliation:

1. Pharmaceutical and Medicinal Chemistry Institute of Pharmacy and Food Chemistry Julius-Maximilians-University of Würzburg Am Hubland 97074 Würzburg Germany

2. Comprehensive Heart Failure Center University Hospital of Würzburg Am Schwarzenberg 15 97078 Würzburg Germany

3. Department of Nuclear Medicine University Hospital of Würzburg Oberdürrbacher Straße 6 97080 Würzburg Germany

4. Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama University 2-5-1 Shikata-cho, Kita-ku Okayama Japan

5. Department of Nuclear Medicine University Hospital of Augsburg Stenglinstraße 2 86156 Augsburg Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000942

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