Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential-Reference-Cited by-同舟云学术

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Published:2021-01-20 Issue:6 Volume:16 Page:1034-1046
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Polomski Marion¹,Brachet‐Botineau Marie²,Juen Ludovic¹,Viaud‐Massuard Marie‐Claude¹,Gouilleux Fabrice²,Prié Gildas¹^ORCID

Affiliation:

1. Equipe IMT “Innovation Moléculaire et Thérapeutique” – GICC EA7501 Université de Tours-Labex SYNORG Faculté de Pharmacie 31 av. Monge 37200 Tours France

2. Equipe LNOx “Niche Leucémique & Métabolisme Oxydatif” – GICC ERL 7001 CNRS Université de Tours Faculté de Médecine Bâtiment Dutrochet, 10bis bvd Tonnellé 37032 Tours France

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000841

Reference49 articles.

1. STAT5 signaling in normal and pathologic hematopoiesis

2. Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways

3. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

4. Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

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1. Targeting Proliferation Signals and the Cell Cycle Machinery in Acute Leukemias: Novel Molecules on the Horizon;Molecules;2023-01-26

2. Fast Transition Metal‐Free Synthesis of Functionalized Oxindoles and Dihydroquinoline‐2‐ones Under Microwave Irradiation;European Journal of Organic Chemistry;2022-11-24

3. Perspectives of herbs and their natural compounds, and herb formulas on treating diverse diseases through regulating complicated JAK/STAT signaling;Frontiers in Pharmacology;2022-10-17

4. Nucleophilic Addition/Electrocyclization Strategy toward Polyheterocyclic-Fused Quinoline-2-thiones in Green Solvent;The Journal of Organic Chemistry;2022-09-12