Bicyclic Imidazolium Inhibitors of Gli Transcription Factor Activity-Reference-Cited by-同舟云学术

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Bicyclic Imidazolium Inhibitors of Gli Transcription Factor Activity

Published:2020-05-26 Issue:12 Volume:15 Page:1044-1049
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Hom Marisa E.¹,Ondrus Alison E.¹²,Sakata‐Kato Tomoyo¹³,Rack Paul G.¹⁴,Chen James K.¹⁵⁶^ORCID

Affiliation:

1. Department of Chemical and Systems BiologyStanford University 269 Campus Dr., CCSR 3155 Stanford CA 94305 USA

2. Present address: Division of Chemistry and Chemical EngineeringCalifornia Institute of Technology Pasadena CA 91125 USA

3. Present address: Global Health Drug Discovery Institute Beijing 100192 China

4. Present address: Thermo Fisher Scientific Carlsbad CA 92008 USA

5. Department of Developmental BiologyStanford University 269 Campus Dr., CCSR 3155 Stanford CA 94305 USA

6. Department of ChemistryStanford University 269 Campus Dr., CCSR 3155 Stanford CA 94305 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000169

Reference33 articles.

1. Mutations affecting segment number and polarity in Drosophila

2. The GLI gene is a member of the Kruppel family of zinc finger proteins

3. GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity.

4. Evidence for the direct involvement of TrCP in Gli3 protein processing

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3. Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1;2022-08-16

4. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1;Nature Chemical Biology;2022-07-04

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