Repurposing of 8‐Hydroxyquinoline‐Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors-Reference-Cited by-同舟云学术

Repurposing of 8‐Hydroxyquinoline‐Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors

Published:2022-02-03 Issue:5 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Gajic Mihajlo¹²^ORCID,Knez Damijan³^ORCID,Sosič Izidor³^ORCID,Mravljak Janez³^ORCID,Meden Anže³^ORCID,Košak Urban³,Leitzbach Luisa²^ORCID,George Sven⁴,Hofmann Bettina⁴,Zivkovic Aleksandra²^ORCID,Steinhilber Dieter⁴^ORCID,Stark Holger²^ORCID,Gobec Stanislav³^ORCID,Smelcerovic Andrija⁵^ORCID,Anderluh Marko³^ORCID

Affiliation:

1. Department of Pharmacy Faculty of Medicine University of Nis Blvd. Dr. Zorana Djindjica 81 18000 Nis Serbia

2. Institute of Pharmaceutical and Medicinal Chemistry Heinrich Heine University Düsseldorf Universitätsstr. 1 40225 Duesseldorf Germany

3. Department of Pharmaceutical Chemistry Faculty of Pharmacy University of Ljubljana Askerceva 7 1000 Ljubljana Slovenia

4. Institute of Pharmaceutical Chemistry Goethe-University of Frankfurt Max-von-Laue Str. 9 60438 Frankfurt/Main Germany

5. Department of Chemistry Faculty of Medicine University of Nis Blvd. Dr. Zorana Djindjica 81 18000 Nis Serbia

Funder

Javna Agencija za Raziskovalno Dejavnost RS

European Cooperation in Science and Technology

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100694

Reference56 articles.

1. DNase I mediates internucleosomal DNA degradation in human cells undergoing drug-induced apoptosis

2. Characterization of Human DNase I Family Endonucleases and Activation of DNase γ during Apoptosis

3. Androgen Ablation Leads to an Upregulation and Intranuclear Accumulation of Deoxyribonuclease I in Rat Prostate Epithelial Cells Paralleling Their Apoptotic Elimination

4. Trashing the genome: the role of nucleases during apoptosis

5. DNase I behaves as a transcription factor which modulates Fas expression in human cells

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