The Evaluation of <scp>l</scp> ‐Tryptophan Derivatives as Inhibitors of the <scp>l</scp> ‐Type Amino Acid Transporter LAT1 (SLC7A5)-Reference-Cited by-同舟云学术

The Evaluation of l ‐Tryptophan Derivatives as Inhibitors of the l ‐Type Amino Acid Transporter LAT1 (SLC7A5)

Published:2022-08-10 Issue:17 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Graff Julien¹,Müller Jennifer¹^ORCID,Sadurní Anna¹^ORCID,Rubin Matthias²,Canivete Cuissa Inês André¹,Keller Claudia¹,Hartmann Marco¹,Singer Simon²,Gertsch Jürg²^ORCID,Altmann Karl‐Heinz¹^ORCID

Affiliation:

1. Department of Chemistry and Applied Biosciences ETH Zürich, HCI H405 Vladimir-Prelog-Weg 4 8093 Zürich Switzerland

2. Institute of Biochemistry and Molecular Medicine University of Bern Bühlstrasse 28 3012 Bern Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200308

Reference49 articles.

1. Role of amino acid transport and countertransport in nutrition and metabolism.

2. Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

3. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

4. Human LAT1, a Subunit of System L Amino Acid Transporter: Molecular Cloning and Transport Function

5. Activation of system L heterodimeric amino acid exchangers by intracellular substrates

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