Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation-Reference-Cited by-同舟云学术

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

Published:2014-10-10 Issue:3 Volume:112 Page:521-535
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Fan Yuzhou¹²,Jimenez Del Val Ioscani³,Müller Christian²,Wagtberg Sen Jette²,Rasmussen Søren Kofoed²,Kontoravdi Cleo³,Weilguny Dietmar²,Andersen Mikael Rørdam¹

Affiliation:

1. Network Engineering of Eukaryotic Cell Factories; Department of Systems Biology; Technical University of Denmark; Building 223 2800 Kgs Lyngby Denmark

2. Symphogen A/S; Pederstrupvej 93; 2750 Ballerup Denmark

3. Center for Process Systems Engineering; Department of Chemical Engineering; Imperial College London; London UK

Funder

Danish Ministry of Science, Innovation and Higher Education

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference76 articles.

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2. Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells;Ahn;Biotechnol Bioeng,2008

3. Advances in improving mammalian cells metabolism for recombinant protein production;Altamirano;Electron J Biotechnol,2013