Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice-Reference-Cited by-同舟云学术

Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice

Published:2020-12-12 Issue:2 Volume:17 Page:149-163
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Audrain Mickael¹^ORCID,Haure‐Mirande Jean‐Vianney¹^ORCID,Mleczko Justyna¹,Wang Minghui²,Griffin Jennifer K.³,St George‐Hyslop Peter H.³,Fraser Paul³,Zhang Bin²,Gandy Sam¹⁴⁵^ORCID,Ehrlich Michelle E.¹²^ORCID

Affiliation:

1. Department of Neurology Icahn School of Medicine at Mount Sinai New York New York USA

2. Department of Genetics and Genomic Sciences and Icahn Institute of Genomic Sciences Icahn School of Medicine at Mount Sinai New York New York USA

3. Tanz Centre for Research in Neurodegenerative Diseases University of Toronto Toronto ON Canada

4. National Institute on Aging‐Designated Alzheimer's Disease Research Center and Department of Psychiatry Icahn School of Medicine at Mount Sinai New York New York USA

5. Research and Development James J. Peters Veterans Affairs Medical Center Bronx New York USA

Funder

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12256

Reference63 articles.

1. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

2. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

3. Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

4. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

5. Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes

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