Identifying the differences in mechanisms of mycophenolic acid controlling fucose content of glycoproteins expressed in different CHO cell lines
Author:
Affiliation:
1. Cell Culture Development; Biogen; 5000 Davis Drive Research Triangle Park North Carolina 27709
2. Cell Culture Development; Biogen; Cambridge Massachusetts 02142
Funder
Biogen New Technology Initiative Committee
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/bit.25995/fullpdf
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3. Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII;Davies;Biotechnol Bioeng,2001
4. The therapeutic monoclonal antibody market;Ecker;MAbs,2015
5. Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I;Elbein;J Biol Chem,1990
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