Combinatorial effects of azacitidine and trametinib on NRAS ‐mutated melanoma-Reference-Cited by-同舟云学术

Combinatorial effects of azacitidine and trametinib on NRAS ‐mutated melanoma

Published:2021-12-06 Issue: Volume: Page:
ISSN:1545-5009
Container-title:Pediatric Blood & Cancer
language:en
Short-container-title:Pediatric Blood & Cancer

Author:

Hanft Klara‐Maria¹,Hamed Ebrahem²³,Kaiser Max²,Würtemberger Julia²,Schneider Michaela²,Pietsch Torsten⁴,Feige Ursula⁵,Meiss Frank⁶,Krengel Sven⁷,Niemeyer Charlotte²⁸,Hettmer Simone²⁸⁹^ORCID

Affiliation:

1. Division of General Pediatrics, Department of Pediatric and Adolescent Medicine University Medical Center Freiburg, University of Freiburg Freiburg Germany

2. Division of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine University Medical Center Freiburg, University of Freiburg Freiburg Germany

3. Faculty of Biology University of Freiburg Freiburg Germany

4. Department of Neuropathology, DGNN Brain Tumor Reference Center University of Bonn Medical Centre Bonn Germany

5. Department of Neuroradiology University Medical Center Freiburg, University of Freiburg Freiburg Germany

6. Department of Dermatology, Venerology and Allergology University Medical Center Freiburg Freiburg Germany

7. Dermatological Group Practice Lübeck Germany

8. Comprehensive Cancer Centre Freiburg (CCCF) Medical Center – University of Freiburg Freiburg Germany

9. Spemann Graduate School of Biology and Medicine (SGBM) Freiburg Germany

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pbc.29468

Reference38 articles.

1. Multiple Congenital Melanocytic Nevi and Neurocutaneous Melanosis Are Caused by Postzygotic Mutations in Codon 61 of NRAS

2. Spectrum of central nervous system abnormalities in neurocutaneous melanocytosis

3. MEK inhibition appears to improve symptom control in primary NRAS-driven CNS melanoma in children

4. Case Reports of Fatal or Metastasizing Melanoma in Children and Adolescents: A Systematic Analysis of the Literature

5. Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor

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