Transmembrane Transporter Constructed from PlatinumMetal‐organic Cage-Reference-Cited by-同舟云学术

Transmembrane Transporter Constructed from PlatinumMetal‐organic Cage

Published:2023-09 Issue:9 Volume:88 Page:
ISSN:2192-6506
Container-title:ChemPlusChem
language:en
Short-container-title:ChemPlusChem

Author:

Hu Xinyu¹^ORCID,Yue Bangkun¹,Chen Chen²,Zong Wei³,Li Sisi⁴,Yang Haishen⁵^ORCID,Hou Yali⁶^ORCID,Zhang Jian¹

Affiliation:

1. Key Laboratory of Micro-Nano Optoelectronic Devices (Wenzhou), College of Electrical and Electronic Engineering Wenzhou University Wenzhou 325035 China

2. Zhejiang Marine Aquaculture Research Institute Wenzhou 325005 China

3. College of Chemistry and Chemical Engineering Qiqihar University Qiqihar 161006 China

4. Ruian Graduate College Wenzhou University Wenzhou 325035 China

5. Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power College of Environmental and Chemical Engineering Shanghai University of Electric Power Shanghai 200090 China

6. State Key Laboratory for MechanicalBehavior of Materials School of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 China

Abstract

AbstractA perylene diimide‐based metal‐organic cage (MOC4c) was found to be an efficient transmembrane transporter for ions and small molecules through the internal cavity of the cage. MOC4c could selectively transport different anions, as evidenced by vesicle‐based fluorescenceassays and planar lipid bilayer‐based current recordings.Furthermore, MOC4c appears tofacilitate calcein transport across the lipid bilayer membrane of a livingcell, suggesting that MOC4c could be used as a biologicaltool for small molecule drugstransmembrane transportation.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Science and Technology Commission of Shanghai Municipality

Publisher

Wiley

Subject

General Chemistry

Reference42 articles.

1. Ion Channels for Communication Between and Within Cells (Nobel Lecture)

2. Aquaporin Water Channels (Nobel Lecture)

3. Transport mechanisms in nanopores and nanochannels: can we mimic nature?

4. Synthetic Ion Channels: From Pores to Biological Applications

5. Transport Across Membranes