Discounting phase 2 results when planning phase 3 clinical trials
Author:
Affiliation:
1. Pfizer Limited; Ramsgate Road Sandwich UK CT13 9NJ
2. JB Stats Ltd.; Reading UK
3. Pfizer Inc; Kalamazoo MI 49009 USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/pst.1521/fullpdf
Reference14 articles.
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2. Adapting the sample size planning of a phase III trial based on phase II data;Wang;Pharmaceutical Statistics,2006
3. Assurance in clinical trial design;O'Hagan;Pharmaceutical Statistics,2005
4. A three-outcome design for randomized comparative phase II clinical trials;Hong;Statistics in Medicine,2007
5. Optimal two-stage designs for single arm phase II cancer trials;Shuster;Journal of Biopharmaceutical Statistics,2002
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