Bioactivation and Toxicity of Acetaminophen in a Rat Hepatocyte Micropatterned Coculture System-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Bioactivation and Toxicity of Acetaminophen in a Rat Hepatocyte Micropatterned Coculture System

Published:2013-07 Issue: Volume: Page:n/a-n/a
ISSN:1095-6670
Container-title:Journal of Biochemical and Molecular Toxicology
language:en
Short-container-title:J Biochem Mol Toxicol

Author:

Ukairo Okechukwu¹,McVay Michael¹,Krzyzewski Stacy¹,Aoyama Simon¹,Rose Kelly²,Andersen Melvin E.²,Khetani Salman R.³,LeCluyse Edward L.²

Affiliation:

1. Hepregen Corporation; Medford; MA; 02155; U.S.A

2. The Hamner Institutes for Health Sciences; Research Triangle Park; NC; 27709; U.S.A

3. Mechanical and Biomedical Engineering; Colorado State University; Fort Collins; CO; 80523-1374; U.S.A

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Toxicology,Molecular Biology,Molecular Medicine,Biochemistry,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbt.21512/fullpdf

Reference27 articles.

1. Deleterious effects of reactive metabolites;Attia;Oxid Med Cell Longevity,2010

2. Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery;Teffera;Chem Res Toxicol,2010

3. Bioactivation of nevirapine to a reactive quinone methide: implications for liver injury;Sharma;Chem Res Toxicol,2012

4. Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? an analysis of 18 drugs with consideration of intrinsic clearance and daily dose;Obach;Chem Res Toxicol,2008

5. Predicting drug-drug interactions from in vitro drug metabolism data: challenges and recent advances;Obach;Curr Opin Drug Discovery Dev,2009

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. How to reduce risk of drug induced liver toxicity from the beginning;Overcoming Obstacles in Drug Discovery and Development;2023

2. Engineered liver tissue in vitro to mimic liver functions and its biomedical applications;Materials Advances;2022

3. A microfluidic 3D hepatocyte chip for hepatotoxicity testing of nanoparticles;Nanomedicine;2019-08

4. Liver safety evaluation of endothelin receptor antagonists using HepatoPac ® : A single model impact assessment on hepatocellular health, function and bile acid disposition;Journal of Applied Toxicology;2019-05-27

5. The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development;ILAR Journal;2016-12

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3