Neuregulin-1 promotes remyelination and fosters a pro-regenerative inflammatory response in focal demyelinating lesions of the spinal cord

Author:

Kataria Hardeep1,Alizadeh Arsalan1,Shahriary Ghazaleh M.1,Saboktakin Rizi Shekoofeh1,Henrie Ryan1,Santhosh Kallivalappil T.1,Thliveris James A.2,Karimi-Abdolrezaee Soheila1ORCID

Affiliation:

1. Regenerative Medicine Program, Department of Physiology and Pathophysiology; Spinal Cord Research Centre, Rady Faculty of Health Sciences University of Manitoba; Winnipeg Manitoba Canada

2. Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences; University of Manitoba; Winnipeg Manitoba Canada

Funder

Canadian Institutes of Health Research

Multiple Sclerosis Society of Canada

Research Manitoba

Rick Hansen Institute

U of M GETS Program, Max Rady College of Medicine, University of Manitoba

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference94 articles.

1. Myelin damage and repair in pathologic CNS: Challenges and prospects;Alizadeh;Frontiers in Molecular Neuroscience,2015

2. Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury;Alizadeh;Glia,2017

3. Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury;Alizadeh;Journal of Physiology,2016

4. Oligodendrocyte fate after spinal cord injury;Almad;Neurotherapeutics,2011

5. Multiple extracellular signals are required for long-term oligodendrocyte survival;Barres;Development,1993

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