Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648

Author:

Hinrichsen Inga1,Ackermann Anne1,Düding Tonja1,Graband Annika1,Filmann Natalie2,Plotz Guido1,Zeuzem Stefan1,Brieger Angela1ORCID

Affiliation:

1. Medical Clinic I; Biomedical Research Laboratory; Goethe-University; Frankfurt a.M. Germany

2. Institute of Biostatistics and Mathematical Modeling; Goethe University Frankfurt; Germany

Funder

Goethe-Universität Frankfurt am Main

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference30 articles.

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2. http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx 2012

3. Disease-associated repeat instability and mismatch repair;Schmidt;DNA Repair (Amst),2016

4. Colorectal cancer due to deficiency in DNA mismatch repair function: a review;Bellizzi;Adv Anat Pathol,2009

5. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer;Boland;Cancer Res,1998

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