Biglycan Intensifies ALK5-Smad2/3 Signaling by TGF-β1and Downregulates Syndecan-4 in Cultured Vascular Endothelial Cells

Author:

Hara Takato1,Yoshida Eiko1,Shinkai Yasuhiro2,Yamamoto Chika3,Fujiwara Yasuyuki4,Kumagai Yoshito2,Kaji Toshiyuki1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Department of Environmental Health; Tokyo University of Science; 2641 Yamazaki Noda 278-8510 Japan

2. Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Science; University of Tsukuba; 1-1-1 Tennodai Tsukuba 305-8575 Japan

3. Faculty of Pharmaceutical Sciences, Department of Environmental Health; Toho University; 2-2-1 Miyama Funabashi 274-8510 Japan

4. Department of Environmental Health, School of Pharmacy; Tokyo University of Pharmacy and Life Sciences; 1432-1 Horinouchi Hachioji 192-0392 Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

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